Arthritis affects around 10 million people in the UK, according to the NHS. The most common types are osteoarthritis and rheumatoid arthritis. There is no cure for arthritis, but painkillers and anti-inflammatories can be taken to help reduce pain and relieve symptoms. However, some medicines such as non-steroidal anti-inflammatory drugs can have undesirable side effects. If you are struggling to find arthritis medication that works for you, you could consider the following five lesser-known natural supplements, as recommended by the Arthritis Foundation.
SAM-e
SAM-e acts as a pain reliever, has anti-inflammatory properties and may stimulate cartilage growth. It also affects neurotransmitters, such as serotonin, which reduce pain perception.
Two studies have shown SAM-e to relieve osteoarthritis symptoms as effectively as NSAIDs, but with fewer side effects and more prolonged benefit.
Gamma linolenic acid

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GLA is an omega-6 fatty acid that the body converts into anti-inflammatory chemicals.
In one trial, 56 patients with active rheumatoid arthritis showed “significant” improvement in joint pain, stiffness and grip strength after six months and “progressive” improvement in control of disease activity after one year.
A smaller study found a combination of GLA and fish oil significantly reduced the need for conventional pain relievers.
Cat’s claw
Cat’s claw is an anti-inflammatory that inhibits tumour necrosis factor, which is a target of powerful rheumatoid arthritis drugs.
A small 2002 trial showed cat’s claw reduced joint pain and swelling by more than 50 per cent compared with placebo.
Capsaicin
Capsaicin temporarily reduces substance P, a pain transmitter. Its pain-relieving properties have been shown in “many studies”, including a 2010 study revealing a 50 per cent reduction in joint pain after three weeks of use.
Boswellia serrate (Indian frankincense)
The active components, known as Boswellic acids, have anti-inflammatory and pain-relieving properties, and may also help prevent cartilage loss and inhibit the autoimmune process.
In a 2008 study, an extract of Boswellia serrate “significantly” improved osteoarthritis pain and function within seven days. An Indian study also revealed it slowed cartilage damage after three months of use.
“Talk to your doctor before taking a supplement so you understand the potential side effects and interactions with your medication,” advises the Arthritis Foundation.