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Novel Blue-Green Hue ‘Olo’ Perceived by Human Retina
In a groundbreaking experiment, involving cutting-edge technology, five individuals have experienced a vivid blue-green color, dubbed ‘olo’, previously unknown to human perception. This achievement stems from a sophisticated device with the potential to revolutionize vision for those with certain forms of color blindness, potentially enabling them to perceive the full spectrum of colors.
Understanding Color Perception in the Retina
Human color perception is orchestrated by the retina, situated at the back of the eye. Typically, the retina houses three types of photoreceptor cone cells – designated as S, M, and L cones. These specialized cells are sensitive to different wavelengths of light, absorbing blue, green, and red light respectively. Upon light detection, these cone cells transmit signals to the brain, which interprets them as color. When we observe colors in the blue-green part of the visible spectrum, multiple types of cone cells are concurrently activated due to the overlapping nature of their light wavelength detection ranges.
The Innovation of Laser Stimulation for Cone Cells
Driven by curiosity, Ren Ng, a researcher at the University of California, Berkeley, investigated the color sensation humans might experience if only a single type of cone cell were activated within this spectral region. His inquiry was sparked by the ‘Oz’ device, a creation of other scientists studying ocular function. This device employs a laser capable of selectively stimulating individual cone cells in the retina.
Experimentation with Enhanced ‘Oz’ Device
Collaborating with the Oz device creators, Ng and his team refined the technology to deliver targeted light stimulation to a small area of approximately 1000 cone cells within the retina. According to Ng, stimulating a solitary cone cell does not produce a sufficient signal to trigger color perception. The upgraded device facilitated the stimulation of a cluster of these cells.
The Discovery of ‘Olo’: A Super-Intense Teal
The scientists tested this enhanced device on five participants. In a controlled setting, they selectively stimulated only the M cone cells within a localized area of one eye, while the other eye remained closed. Participants reported perceiving a blue-green hue, which the research team termed ‘olo.’ This novel color was described as significantly more intense than any color encountered previously. “It’s challenging to articulate; it possesses a remarkable brilliance,” Ng, who has also personally witnessed olo, stated.

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Verifying ‘Olo’ Through Color-Matching Tests
To validate these subjective reports, participants engaged in a color-matching experiment. Subjects were presented with olo and a secondary adjustable color, controllable via a dial across the standard visible spectrum. Their task was to fine-tune the adjustable color to achieve the closest possible match to olo. Consistently, participants adjusted the dial to an intense teal shade, reinforcing the subjective descriptions of olo.
Intensity Confirmation Through Light Dilution
In a subsequent phase of the experiment, participants used a dial to introduce white light to both olo and a separate vivid teal color, aiming to achieve an even closer perceptual match. Notably, all participants chose to dilute olo, further substantiating the finding that olo is the more saturated and intense of the two colors.
Potential Medical Applications for Vision Enhancement
Andrew Stockman, from University College London, characterized the study as both “intriguing” and potentially significant for medical advancement. He suggested that this technology could offer a pathway for individuals with red-green color blindness to experience typical vision. Red-green color blindness often arises when M and L cone cells are activated by very similar light wavelengths, making it difficult to differentiate between red and green. Selectively stimulating one type of cone cell over the other could broaden the range of perceptible hues. However, Stockman emphasized that clinical trials are necessary to validate this potential application and explore therapeutic benefits for vision impairment.