Orton won the US title for the first time in his 16-year career last Sunday at Fastlane when he beat Roode.
Mahal then attacked the new champion but was fought off by the former title holder who took both competitors out with a Glorious DDT.
Last Tuesday night on Smackdown, The Glorious One announced he wants to invoke his rematch clause at WrestleMania and then lost to Mahal – both stars then suffered a vicious RKO from Orton.
The Wrestling Observer Newsletter, as reported by Give Me Sport, are expecting all three men to compete in a Triple Threat Match for the US title at Mania.
Roode will be competing on his very first WrestleMania after making a name for himself on TNA where he became a two-time TNA World Heavyweight Champion.
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That will be the second Tripe Threat Match of the night as The Miz is scheduled to defend the Intercontinental title against Finn Balor and Seth Rollins on April 8 in New Orleans, Louisiana.
The Miz suffered a pinfall loss to both of his challengers on RAW.
Balor has the most momentum so far as he also defeated Rollins last Monday night.
The Demon King beat Rollins on the first ever Universal title match at Summerslam 2016.