Puppies treated with CRISPR show improvement from muscular dystrophy

By Chelsea Whyte

CRISPR gene-editing has been used to improve muscle function in dogs with a Duchenne muscular dystrophy (DMD)-like condition – and eventually the technique might lead to a treatment for humans too. The study represents the first use of CRISPR gene-editing in a living large animal.

People with DMD have a genetic mutation that makes them unable to produce dystrophin, a protein that maintains muscle structure and function. The condition can result in heart or lung failure. In 2010, Richard Piercy at the …

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