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Study Highlights Potential Nutrient Deficiencies in Vegan Diets
A recent study suggests that approximately half of vegans may suffer from deficiencies in crucial nutrients, potentially increasing their risk of health issues such as muscle wastage. The research, focusing on long-term vegans, revealed significant shortcomings in essential amino acids, despite adequate overall protein intake, raising concerns about the nutritional completeness of vegan diets.
Research Uncovers Amino Acid Shortcomings
Experts conducted an analysis of the dietary habits of nearly 200 long-term vegans in New Zealand. The findings indicated that around 50% of participants exhibited a deficiency in lysine and leucine, two vital amino acids that serve as the fundamental components of protein.
Lysine and Leucine: Essential for Bodily Functions
These critical nutrients, abundantly present in animal-derived proteins such as meat and eggs, play a crucial role in muscle development and maintenance, as well as other essential bodily functions like energy production from fat. The study emphasizes the importance of these amino acids for overall health and well-being.
Adequate Protein Intake, Yet Deficiencies Persist
Surprisingly, these nutritional gaps were observed even though a significant majority—three out of four—of the vegan participants met the recommended daily guidelines for plant-based protein consumption issued by health authorities. This suggests that simply consuming enough plant protein may not guarantee sufficient intake of all essential amino acids.
Limited Absorption from Plant Sources
Scientists from Massey University explained that while the vegans appeared to consume sufficient protein on paper, their bodies were not effectively absorbing adequate quantities of lysine and leucine. This is attributed to the limited bioavailability of these amino acids in plant-based foods, where only a fraction of the already lower levels are absorbed, with the remainder being excreted.

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Potential Hazards of Restrictive Veganism
Patricia Soh, the lead author of the study, stated that the results underscore some of the potential risks associated with adopting vegan diets.
‘Vegan diets, being the most restrictive form of plant-based eating, depend entirely on plant sources for all nutritional requirements,’ Soh noted.
‘Sustained deficiencies in these essential nutrients can have detrimental effects on bodily functions, including the maintenance of muscle mass.’
She further cautioned that these risks could be amplified among vulnerable populations of vegans, such as elderly individuals.
Plant Foods Contain Lower Levels
While plant-based foods, including beans, peas, nuts, and seeds, do contain lysine and leucine, their levels are considerably lower compared to equivalent portions of animal protein. This difference in amino acid density can contribute to the observed deficiencies in vegans.
Potential Downsides of Vegan Diets
Nutrient Deficiencies and Health Concerns
Transitioning to a completely plant-based diet may lead to tiredness or skin breakouts, dieticians have cautioned. Eliminating animal products can result in a lack of essential vitamins, such as B12, and insufficient protein intake.
- Vitamin B12 Deficiency: Found in milk and eggs, inadequate B12 can cause fatigue and negatively affect mental well-being.
- Vitamin D Deficiency: Predominantly found in animal products like oily fish, deficiency can impair bone development and cause pain.
- Protein Deficiency: Insufficient protein, typically obtained from dairy, fish, eggs, and meat, may hinder growth in children and contribute to acne.
- Iron Deficiency: Lack of iron from red meat and liver can lead to anaemia, causing fatigue and heart palpitations.
- Iodine Deficiency: Primarily found in seafood, iodine deficiency is common in vegan diets and is vital for maintaining a healthy metabolism.
While plant-based diets can provide these nutrients, careful meal planning or supplementation is crucial to ensure adequate intake, especially when transitioning from a diet rich in animal products. Furthermore, there’s a misconception that all vegan products are inherently healthier. Analysis reveals many vegan alternatives contain higher levels of salt, sugar, and fat than the animal products they replace.
Recommendations for Vegans
Ms. Soh emphasized the need for further research focused on strategies to enhance lysine and leucine intake among vegans.
‘Incorporating legumes, nuts, and seeds is beneficial for supporting overall protein consumption and increasing lysine and leucine levels in a vegan diet,’ she advised.
Study Limitations and Alternative Perspectives
However, other experts have pointed out limitations within the study that should be considered.
Professor Tom Sanders, a nutrition and dietetics expert at King’s College London, noted that the absence of an omnivore control group in the analysis limits comparative conclusions. He also highlighted the study’s failure to account for the potential role of gut bacteria in lysine production.
Study Methodology
The research, published in PLOS One, involved analyzing four-day food diaries maintained by 193 long-term vegans. Researchers utilized these records to calculate amino acid consumption and estimate the amount extracted and lost during digestion.
Findings on Protein vs. Amino Acid Intake
The study revealed that while 80% of men and 73% of women consumed sufficient overall protein, the proportion meeting the specific requirements for lysine and leucine dropped to approximately half when digestion was factored in.
The researchers established a threshold of 59mg of leucine and 45mg of lysine per gram of protein consumed, based on dietary guidelines from American and New Zealand recommendations.
Considerations Regarding Food Diary Studies
Studies relying on food diaries are subject to inherent limitations, as they depend on participants’ accurate recall and reporting of food intake, including portion sizes. Food diaries also provide a snapshot of dietary habits and may not fully represent an individual’s typical long-term diet.
Wider Health Concerns Associated with Veganism
Nutritionists have previously cautioned that adopting a vegan lifestyle may present various health consequences.
These include deficiencies in:
- Vitamin B12
- Vitamin D
- Iron
- Iodine
Vegan diets can provide these nutrients with careful planning or supplements. As of 2024, the UK vegan population is estimated at 2.5 million, approximately 3.6% of the total population.