Mr Pomepo, 58, told his wife Susan that he had to change.
He told The New York Post: “I started exercising, not every day, but nearly every day, and eating right and the weight just started to come off.”
Pompeo said that he also invested in a home gym in his basement with some dumbbells and an elliptical machine.
He added: “I tried to get down there five, six times a week and stay at it for a half-hour or so. And that was nothing scientific.
“There was no trainer, there was no dietician. It was just me.”
The West Point graduate started putting on the pounds after he was elected to Congress as a representative for Kansas in 2010.
However, Mr Pompeo admits that maintaining a healthy weight has been a “lifetime struggle” for him.
Discipline has also been important and that has involved changing his diet, ditching the cheeseburgers and sugary treats for more balanced food choices.
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He said: “I put on almost a hundred pounds over the course of 10, 11 years — years that coincided with my foot injury — so I told myself that was the reason I gained so much weight.”
Since leaving the Trump administration Mr Pompeo has contributed to Fox News, worked as a senior counsel for global affairs at the American Center for Law and Justice, and chairs the Calvary PAC, an organization dedicated to electing conservative candidates to the US House and Senate.
Laughing off talk of a 2024 Presidential bid he wants to spend time with his “enormously supportive” wife and family as well as being around to hopefully enjoy being a Grandad.