Southampton make one change from last weekend’s draw at the Etihad. Jack Stephens, who suffered a bad knee injury in that game, is replaced by Mohammad Salisu.
Bruno Lage has dropped Adama Traore, Ruben Neves and Trincao in response to that defeat at home to Brentford. Leander Dendoncker, Daniel Podence and Hwang Hee-chan come in.
Southampton (4-4-2) McCarthy; Livramento, Bednarek, Salisu, Walker-Peters; Elyounoussi, Romeu, Ward-Prowse, Redmond; Adams, Armstrong.
Substitutes: Forster, Lyanco, Perraud, Valery, Djenepo, Tella, Diallo, Long, Broja.
Wolves (3-4-3) Sa; Kilman, Coady, Saiss; Semedo, Moutinho, Dendoncker, Marcal; Podence, Hwang, Jimenez.
Substitutes: Moulden, Ruddy, Hoever, Boly, Neves, Cundle, Trincao, Traore, Fabio Silva.
Referee Andy Madley.