Starting XI
Jose Mourinho handed a maiden Premier League appearance to Japhet Tanganga against champions elect Liverpool.
The 20-year-old centre-half has only played in a Carabao Cup game at Colchester but was thrown in against the Reds, with Danny Rose returning from an injury.
Liverpool made one change from their last league outing, with Alex Oxlade-Chamberlain replacing the injured James Milner.
Tottenham XI: Gazzaniga, Aurier, Tanganga, Sanchez, Alderweireld, Rose, Winks, Eriksen, Moura, Alli, Son.
Subs: Vorm, Vertonghen, Dier, Skipp, Lo Celso, Lamela, Sessegnon.
Liverpool XI: Alisson, Alexander-Arnold, Gomez, Van Dijk, Robertson, Oxlade-Chamberlain, Henderson, Wijnaldum, Salah, Firmino, Mane.
Subs: Adrian, Williams, Phillips, Lallana, Minamino, Shaqiri, Origi.