Choose your 2019 Breakthrough of the Year!

What has been the most significant scientific development this year? Science’s reporters and editors are debating that question as they home in on the 2019 Breakthrough of the Year. Their selection, along with nine runners-up, will be announced when the last issue of the year goes online on 19 December.

You can get in on the action! Pick your favorite breakthrough from the candidates below by Monday, 2 December. Then check back after noon on Tuesday, 3 December, when we will start a second round of voting with your four top picks. We will announce the winner—the People’s Choice—along with Science’s choice on 19 December.

Cast your vote today!