Manchester City striker Sergio Aguero netted in his sixth straight match to take his tally to the season to eight goals – one more than Chelsea’s Tammy Abraham.
The Argentina international scored one in an 8-0 rout of struggling Watford at the Etihad on Saturday afternoon.
With Abraham in action against Liverpool on Sunday, Norwich’s Teemu Pukki missed the chance to climb up the standings as Norwich lost 2-0 at Burnley.
Harry Kane took his tally to four goals as Tottenham suffered a 2-1 defeat at Leicester, while Pierre-Emerick Aubameyang will be eager to bag when Arsenal face Aston Villa on Sunday.
Premier League top scorers 2019/20
*updated September 21 7:30pm
Sergio Aguero (Manchester City) – 8 goals, 2 assists
Tammy Abraham (Chelsea) – 7 goals, 0 assists
Teemu Pukki (Norwich City) – 6 goals, 2 assists
Pierre-Emerick Aubameyang (Arsenal) – 5 goals, 0 assists
Raheem Sterling (Manchester City) – 5 goals, 0 assists
Mohamed Salah (Liverpool) – 4 goals, 2 assists
Sadio Mane (Liverpool) – 4 goals, 1 assists
Harry Kane (Tottenham Hotspur) – 4 goals, 1 assists
Callum Wilson (Bournemouth) – 4 goals, 0 assists
Ashley Barnes (Burnley) – 4 goals, 0 assists
Marcus Rashford (Manchester United) – 3 goals, 1 assist
Jamie Vardy (Leicester) – 3 goals, 1 assist
Harry Wilson (Bournemouth) – 3 goals, 0 assists
Sebastien Haller (West Ham) – 3 goals, 0 assists
Mason Mount (Chelsea) – 3 goals, 0 assists
Daniel James (Manchester United) – 3 goals, 0 assists