The final Grand Slam of the year is upon us and the main draw gets underway today with British fans having to stay up until the early hours of the morning to catch all of action.
Novak Djokovic will be bidding to defend his 2018 crown and win his fifth Grand Slam from the last six.
The world No 1 is the man to beat currently, but Rafael Nadal has been strong at Flushing Meadows of late while Daniil Medvedev has the best form of anybody having made three consecutive tour-level finals.
Last year saw Federer slip to a surprise defeat in the fourth round and expect more surprises this year as well with the young players once again looking to make a name for themselves.
US Open order of play: Full Day one schedule
Arthur Ashe Stadium – 5pm (BST) start time
Zarina Diyas vs Ashleigh Barty [2]
Novak Djokovic [1] vs Roberto Carballes Baena
Not before 12am
Serena Williams [8] vs Maria Sharapova
Roger Federer [3] vs Sumit Nagal
Louis Armstrong Stadium – 4pm start time
Tereza Martincova vs Karolina Pliskova [3]
Prajnesh Gunneswaran vs Daniil Medvedev [5]
Saisai Zheng vs Venus Williams
Not before 12am
Stan Wawrinka [23] vs Jannik Sinner
Misaki Doi vs Madison Keys [10]
Grandstand – 4pm start
Marco Trungelliti vs Kei Nishikori [7]
Angelique Kerber [14] vs Kristina Mladenovic
Sam Querrey vs Juan Ignacio Londero
Sofia Kenin [20] vs CoCo Vandeweghe
Court 17 – 4pm start
Johanna Konta [16] vs Daria Kasatkina
Fabio Fognini [11] vs Reilly Opelka
Elina Svitolina vs Whitney Osuigwe
Not before 10pm
Taylor Fritz [26] vs Feliciano Lopez
US Open order of play: Full Day 1 schedule – Williams vs Sharapova, Federer and Djokovic (Image: GETTY)
Serena Williams opens against Maria Sharapova (Image: GETTY)
Court 5 – 4pm start
Eugenie Bouchard vs Anastasija Sevastova
Ekaterina Alexandrova vs Samantha Stosur
Zachary Svajda vs Paolo Lorenzi
Nicolas Jarry vs Milos Raonic [21]
Court 10 – 4pm start
Carolina Garcia [27] vs Ons Jabeur
Adrian Mannarino vs Dan Evans
Gregoire Barriere vs Cameron Norrie
Carolina Dolehide vs Qiang Whang [18]
Court 13 – 4pm start
Tomas Berdych vs Jenson Brooksby
Kwon Soon-Woo vs Hugo Dellien
Viktorija Golubic vs Zhang Shuai [33]
Zhu Lin vs Xin Yu Wang
Court 4 – 4pm start
Petra Martic [22] vs Tamara Zidansek
Monica Niculescu vs Dayana Yastremska [32]
Corentin Moutet vs David Goffin [15]
Yoshihito Nishioka vs Marcos Giron
Roger Federer faces Sumit Nagal (Image: GETTY)
Court 6 – 4pm start
Marton Fucsovics vs Nikoloz Basilashvili [17]
Ivana Jorovic vs Iga Swiatek
Peng Shuai vs Varvara Pechenko
Guido Pella [19] vs Pablo Carrena Busta
Court 7 – 4pm start
Cristian Garin [31] vs Christian Eubanks
Elena Rybakina vs Karolina Muchova
Borna Coric [12] vs Evgeny Donskoy
Caty McNally vs Timea Bacsinszky
Court 8 – 4pm start
Monica Puig vs Rebecca Peterson
Pierre-Ougues Herbert vs Alex de Minaur
Dominik Koepfer vs Jaume Munar
Court 9 – 4pm start
Mariam Bolkvadze vs Bernarda Pera
Jana Cepelova vs Hsieh Su-Wei [29]
Philip Kohlschreiber vs Lucas Pouille [25]
Ricardas Berankis vs Jiri Vesely
Novak Djokovic faces Roberto Carballes Baena in the first round (Image: GETTY)
Court 11 – 4pm start
Thiago Monteiro vs Bradley Klahn
Lauren Davis vs Johanna Larsson
Andreas Seppi vs Grigor Dimitrov
Magdalena Frech vs Laura Siegemund
Court 12 – 4pm start
Denis Kudla vs Janko Tipsarevic
Aliaksandra Sasnovich vs Jennifer Brady
Maria Sakkari [30] vs Camila Giorgi
Jack Sock vs Pablo Cuevas
Court 14 – 4pm start
Ana Bogdan vs Harriet Dart
Margarita Gasparyan vs Priscilla Hon
Laslo Djere vs Miomir Kecmanovic
Hubert Hurkacz vs Jeremy Chardy
Court 15 – 4pm start
Steve Darcis vs Dusan Lajovic [27]
Fiona Ferro vs Daria Gavrilova
Viktoria Kuzmova vs Alison Van Uytvanck
Elliot Benchetrit vs Damir Dzumhur