TEL AVIV (Reuters) – Bristol-Myers Squibb Co and Israel’s Compugen said on Thursday they will collaborate in clinical trials for patients with advanced solid tumors.
FILE PHOTO: Logo of global biopharmaceutical company Bristol-Myers Squibb is pictured at the headquarters in Le Passage, near Agen, France March 29, 2018. REUTERS/Regis Duvignau/File Photo
The trials will evaluate the safety and tolerability of Compugen’s COM701, an investigational antibody, in combination with Bristol-Myers Squibb’s immune checkpoint inhibitor Opdivo.
In conjunction with the collaboration, Bristol-Myers Squibb will invest $12 million in Compugen, purchasing 2,424,243 shares – equal to a 4.1 percent stake – at $4.95 each. The investment represents a 33 percent premium over the average closing price on the last 20 trading days and is expected to close on or about Oct. 12.
Compugen will sponsor an ongoing two-part early stage trial, which includes evaluating the combination of COM701 and Opdivo in four tumor types, including non-small cell lung, ovarian, breast and endometrial cancer. The collaboration is also designed to address potential future combinations.

vCard.red is a free platform for creating a mobile-friendly digital business cards. You can easily create a vCard and generate a QR code for it, allowing others to scan and save your contact details instantly.
The platform allows you to display contact information, social media links, services, and products all in one shareable link. Optional features include appointment scheduling, WhatsApp-based storefronts, media galleries, and custom design options.
Opdivo, approved in over 60 countries, is designed to harness the body’s immune system to help restore anti-tumor immune response.
Reporting by Tova Cohen; Editing by Steven Scheer