Bristol-Myers to invest in Compugen, collaborate in clinical trials

TEL AVIV (Reuters) – Bristol-Myers Squibb Co and Israel’s Compugen said on Thursday they will collaborate in clinical trials for patients with advanced solid tumors.

FILE PHOTO: Logo of global biopharmaceutical company Bristol-Myers Squibb is pictured at the headquarters in Le Passage, near Agen, France March 29, 2018. REUTERS/Regis Duvignau/File Photo

The trials will evaluate the safety and tolerability of Compugen’s COM701, an investigational antibody, in combination with Bristol-Myers Squibb’s immune checkpoint inhibitor Opdivo.

In conjunction with the collaboration, Bristol-Myers Squibb will invest $12 million in Compugen, purchasing 2,424,243 shares – equal to a 4.1 percent stake – at $4.95 each. The investment represents a 33 percent premium over the average closing price on the last 20 trading days and is expected to close on or about Oct. 12.

Compugen will sponsor an ongoing two-part early stage trial, which includes evaluating the combination of COM701 and Opdivo in four tumor types, including non-small cell lung, ovarian, breast and endometrial cancer. The collaboration is also designed to address potential future combinations.

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Opdivo, approved in over 60 countries, is designed to harness the body’s immune system to help restore anti-tumor immune response.

Reporting by Tova Cohen; Editing by Steven Scheer

Our Standards:The Thomson Reuters Trust Principles.
source: reuters.com


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