Karius moved to Besiktas in the summer on a two-year loan deal following his horror show in the Champions League final last season.
But his luck doesn’t seem to have improved at the Turkish heavyweights.
He was left red faced tonight after mis-judging a cross that took a hefty deflection off team-mate Caner Erkin.
Reds boss Jurgen Klopp spent £69m on Alisson from Roma after offloading Karius.
But BT Sport pundit Dean Saunders doesn’t think Karius’ exodus necessarily means his Anfield career is over.
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“Karius cost them against Real Madrid and Klopp will be kicking himself because he should have done something about it before,” Saunders exclusively told Express Sport.
“You don’t want to see that happen to anyone, but the lad’s had to go to Turkey and I think he’s done the right thing.
“Get away, rebuild your confidence and your belief then come back again.
“Maybe in a years time, we’ll say; ‘look he was on the floor, but now he’s shown real mental strength from that set back and come back’.”
Karius faced more criticism in Turkey last month.
A British newspaper claimed the former Mainz star had made comments about female Besiktas supporters.
“I did not have this many fans in England and I can say most seem to be female,” Karius was quoted as saying.
“Whenever I am out and about in Istanbul whoever recognises me wants a photograph.”
However, the Liverpool loanee hit back on social media, insisting he has not undertaken any interviews since arriving in Turkey.
“Since arriving in Turkey I haven’t had any interviews,” he tweeted.
“The news and quotes that have been published are not true.
“That’s something I wanted you to know. Yours, Loris Karius.”