A motorway bridge collapsed on Tuesday near the northern Italian port city of Genoa, local police and fire brigade officials said.
The video, filmed by a resident, shows the moment Ponte Morandi collapsed as various drivers were crossing it.
Part of the bridge remained intact after the collapse.
The moment shocked residents who can be heard in the video screaming “Oh my God. Oh my God.”
The bridge, a part of the A10 motorway, is about 100 metres tall, Italian media say – The Italian ambulance service said there may “dozens of dead” in the incident.
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Italy transport minister said the Genoa motorway bridge collapse seems like an “immense tragedy”.
Italian television showed images of the collapsed bridge, which was built on the A10 toll motorway in the 1960s. Restructuring work on the bridge was carried out in 2016.
Six people have already been extracted alive from the rubble, five of which are in life-threatening conditions.
Eleven people have been confirmed dead, including a child.
The local fire brigade said also victims were likely after the bridge collapsed at around 11:30 a.m. (0930 GMT) during torrential rainfall.
A witness told Sky Italia television he saw “eight or nine” vehicles on the bridge when it collapsed in what he said was an “apocalyptic scene”.
Transport Minister Danilo Toninelli said in a tweet that he was “following with great apprehension what seems like an immense tragedy”.
Authorities have now closed off the motorway A10 Genoa-Savona to Genoa Airport in both directions.
Rail services have also currently been suspended.
The collapse of the bridge is believed to have been caused by a structural failure.
The bridge was named after engineer Riccardo Morandi and was built between 1963 and 1967.
It is one of the major motorway bridges in the region of Liguria.