The latest outbreak of the highly-infections virus comes just days after the government announced a separate flare-up had been contained.
Health officials said dozens of Ebola cases have been recorded in the north east of the country, where fighting between militia groups has already forced more than a million people to flee.
A small number of cases have also been recorded in less than 45 miles from the border with Uganda.
These latest deaths come after an outbreak in the north west of the country, which also killed 33 people, was declared over.
Health authorities say they have no evidence the two outbreaks are connected.
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The World Health Organisation (WHO) has warned the DRC Ebola outbreak is “at the top of the scale” in terms of difficulty responding because of the country’s tropical climate, the remote location of some of the cases and the problem of delivering supplies through territory controlled by armed groups.
A vaccine which can help stop the spread of the virus and contain outbreaks is already in the country, though specialist equipment is required to transport it over long distances.
The so-called ‘cold chain’ required to keep the vaccine at sub-zero temperatures in the sweltering heat of the DRC will be in place this weekend, officials said.
Officials confirmed a new cluster of cases in North Kivu and neighbouring Ituri province – some 1,500 miles from the previous outbreak.
Preliminary laboratory tests on the virus suggest the outbreak is the ‘Zaire’ strain of the Ebola virus.
The strain is the deadliest form of the disease, but it is also the type which the vaccine was designed to combat.
The highly contagious Ebola virus was first discovered in the DRC in the 1970s.
It was named after the Ebola river in the east of the country.
The DRC has suffered nine Ebola flare-ups in the past decade.
The largest known outbreak in 2014-15 affected three countries in west Africa.
Some 28,000 infections and 11,000 deaths were reported in Guinea, Liberia and Sierra Leone.
Those infected typically suffer from fever, headache and debilitating joint and muscle pain.
This is followed by more severe symptoms including fever, haemorrhaging and bloody vomiting.
The highly contagious Ebola virus was first discovered in the DRC in the 1970s. It was named after the Ebola river in the east of the country.