Mr Salvini described the euro as a “German currency” and claimed it had damaged the Italian economy.
Speaking on the sidelines of a rally in Florence, where opposition supporters staged a noisy protest against his party, Mr Salvani said: “It’s clear to everyone that the euro is a mistake for our economy.”
The heavily Eurosceptic Lega Nord is a key member of a centre-right coalition which polls suggest will win most seats on March 4 vote but probably fall short of a working majority.
Mr Salvini, who last month unveiled two prominent anti-euro economists among his party’s candidates, said it was only a matter of time before the euro collapsed and that he was “preparing an emergency exit for the Italians”.
He said: “We don’t have a euro in our pockets. We have a German mark which they called the euro.”
Lega Nord is polling at around 14 percent according to two surveys released this week, around two points behind its main coalition ally Forza Italia led by former prime minister Silvio Berlusconi.
The two leaders have agreed that if the centre-right bloc wins the election, whichever party gets more votes will choose the prime minister and set the policy agenda.
Mr Berlusconi, who wants Italy to remain in the eurozone, is barred from office because of a 2013 tax fraud conviction and has not yet proposed a candidate for prime minister, while Mr Salvini says he will take power of his party comes first.
The Lega Nord manifesto says Italy should leave the European Union unless the fiscal rules set out in the Maastricht Treaty which prepared the ground for the single currency were scrapped.
It says: “We want to remain in the EU only if we can renegotiate all the treaties which limit our full and legitimate sovereignty, in practical terms returning to the European Economic Union which preceded the Maastricht Treaty.”
Mr Berlusconi said Italy should respect the EU’s budget deficit ceiling of three percent of gross domestic product.
Each party in the centre-right bloc, which also includes the small, far-right Brothers of Italy party, has issued its own election programme and the coalition has also published a joint programme containing points they all agree on.