In a video message released today, the allies promised to help make the European Union more “sovereign, united and democratic”.
The bloc’s two most powerful leaders also talked up the prospect of agreeing major reforms to the crisis-hit eurozone.
Mr Macron said: “We want to consolidate and renew our cooperation with a view to moving ahead with a prosperous and competitive Europe.”
Stood alongside the French leader, Mrs Merkel added: “We are doing that in order to bring the people in our countries even closer together.
“And we do it to give the whole of Europe a new boost, to make it even stronger.”
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Their comments will spark horror from Eurosceptics who fear the EU is turning into a federalist superstate and eroding national identity.
The video was released to the mark 55th anniversary of the Elysee treaty, which was signed in 1963 to mark the nations’ post-war reconciliation.
Mrs Merkel and Mr Macron said they had agreed to draw up a new treaty this year.
They want their new agreement to define France and Germany‘s common positions on all key European and international issues.
The leaders also want to boost defence and security cooperation, and draft a joint response to the challenges of uncontrolled immigration.
In a speech in September, days after the German election, the French president had said he wanted to work on a new treaty.
Four months later, Merkel is still trying to form a coalition government, making it hard for her to respond to Mr Macron’s proposals for reform.
Germany’s center-left Social Democrats (SPD) decided on Sunday to start formal coalition talks with Merkel’s Christian Democrats (CDU).