Police in the city said a man suffered serious injuries when an object he picked up off the floor exploded in his hands.
The man has been taken to hospital.
The conditions of the second blast victim is unknown.
Social media reports of further casualties have not been confirmed.
Police said the powerful explosion happened at the Varby Gard metro station in the Huddinge municipality.
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A spokesman said: “Police patrols have encountered a person injured in what is believed to be an explosion.
“After talking to a person who was in the company of the injured party, it appears that the explosion was caused by an object from the ground.”
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