Manchester City will be looking to continue their winning streak, while also maintaining a nice points cushion ahead of their clash with Man Utd.
And there could be some good news squad-wise for manager Pep Guardiola.
That’s because David Silva will be back in contention, while midfielder Leroy Sane will also have a shot at some game time.
It’s still unclear, however, if both Vincent Kompany and Fernandinho will be able to take part.
Andy Carroll and Javier Hernandez remain sidelined for West Ham, who will be looking to pick up as many points as possible.

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The Hammers find themselves in the bottom three, having won just three of their last 25 meetings in all competitions.
West Ham manager David Moyes had this to say on today’s encounter: “I think there’s been moments where we’ve looked okay.
“The players are trying to improve and get better. A lot of our goals are down to individual mistakes.
“This is a big job but it’s a good job. We’ve got a good team.
“I’ve never gone into any game thinking we’ve not got a chance of winning.”
HOW TO WATCH MANCHESTER CITY VS WEST HAM:
Coverage of today’s game between Manchester City and West Ham will be shown live on Sky Sports Main Event (Sky channel 435, Sky HD 401, Virgin channel 511) and Sky Sports Premier League (Sky channel 436, Sky HD 402, Virgin channel 512), with the pre-match build-up starting at 3:30pm and kick-off set for 4:00pm.
This means that all the action can be followed on your desktop or laptop via the Sky Go app, which if you’re an existing customer, is also available on iOS and Android smartphone and tablet devices.
Sky Go is also available on a number of platforms including Amazon Fire devices, iPad, Mac computers and laptops, Playstation 3, PS4 and Xbox One.
The Sky Sports app, available to download on iOS and Android devices, will also be providing live text coverage and updates.
If you’re not currently a Sky Sports customer but can’t stand to miss out on the action, you can add the channels to your box via a NOW TV subscription.
Day passes, which let you add Sky Sports channels for 24 hours, start at £6.99 a day, with a weekly pass starting from £10.99, and no locking in to a contract.
NOW TV doesn’t even require a typical television to use, as it is also available on a NOW TV Box, Chromecast, PS4, PS3, Xbox One, Xbox 360, Roku, LG Smart TV, PC or Mac, and selected mobile and tablet devices.