James Plummer said his sister Laura is struggling to cope behind bars and has started losing hair with stress.
The 33-year-old from Hull was arrested in Cairo after being found to be carrying nearly 300 tramadol tablets and some Naproxen in her suitcase for her Egyptian husband’s bad back.
In her last text to her 70-year-old father Neville, she begged: “I’m in trouble and I need your help.”
He tried to reply but her telephone was off.
Mr Plummer, 31, said his sister, who flies out to visit her husband two to four times a year, thought she was merely doing a “good deed”.

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He said yesterday: “It’s just blown out of proportion completely.
“She’s so by the book, so routine, she just likes her own home comforts, watches Emmerdale every night or things like that, going to bed at nine o’clock every night.”
Mr Plummer said his mother Roberta, 63, and sisters Rachel Plummer, 31, and Jayne Synclair, 40, have travelled to Egypt to visit Laura after her arrest on October 9.
He added: “They say she’s unrecognisable.
“When they have seen her, she’s like a zombie, they said.
“I don’t think she’s tough enough to survive it.
“She has a phobia of using anybody else’s toilet, so let alone sharing a toilet and a floor with everybody else.
“That will be awful for her.
“It’ll be traumatising.”
He added that the family felt “helpless” due to being in a different country, and said of his sister: “It’s awful for Laura… she’s not a tough person at all.
“She’s only small.”
Ms Plummer claims she was forced to confess to drug possession in a 38-page Arabic document before being locked in a tiny cell with dozens of other women.
A Foreign Office spokesman said: “We are supporting a British woman and her family following her detention in Egypt.”