Businessman Andrej Babiš has maintained a consistent lead with the most recent predictions giving him a 12.5 per cent lead over his nearest rival.
If the polls play out in the two-day ballot tomorrow and Saturday, Mr Babiš’s ANO party would win 25 per cent of the national vote and come away with around 67 seats in the country’s legislature.
But even with such a convincing win, he would still need to form a coalition with other parties in order to govern.
The charismatic leader has seen his lead dip slightly, but is still predicted to win convincingly after the votes are counted.
The former finance minister has promised to run the Central European nation “like a family business” and is ardently against the country adopting the euro.
The 63-year-old has tapped in to an anti-EU sentiment in the Czech Republic while on the campaign trail and spoken out against what he perceives as “European meddling”.
Recent surveys in the country show only a third agree the EU is a “good thing” and only 25 per cent want to adopt the euro.
Other ANO policies include tightening up the Czech border and refusing to accept refugees from border nations such as Italy and Greece.
Slovak-born Mr Babiš has a vast business empire which includes farms, chemical plants and two leading Czech newspapers.
He campaigned on an anti-corruption ticket despite concerns over possible conflicts of interests with his companies and being under investigation himself for allegedly illegally receiving EU subsidies at one of his farms.
But he has continually denied the allegation and the scandal appears to have done little to damage his reputation with voters.
An aggregate of polls by agency Median posted on October 16 shows the ANO leading with a quarter of the national vote.
The Social Democratic Party trails in second with 12.5 per cent, and the Community party polls third with 10.5 per cent.
The surveys ranged from 900 to 1,100 respondents, and had a margin of error between 1 and 3.5 per cent.