The Chiefs (4-0) are the only undefeated team in the league after defeating the Washington Redskins in Week 4.
But the Texans (2-2) were also in scintillating form last time out, posting a franchise-record 57 points in their win over the Tennessee Titans.
And Houston’s rookie quarterback Deshaun Watson posted his best game – throwing four touchdown passes.
Many have tipped this to be the Chiefs’ first loss of the season but they have already upset the odds against the New England Patriots.
Either way, it’s expected to be a tasty affair and here is how you can follow the action live.
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How can I watch Kansas City Chiefs vs Washington Redskins live on TV?
The penultimate game of Week 5 in the NFL is live on Sky Sports with coverage starting at 1:00am (BST) today with the match scheduled to begin at 1:30am.
Sky Sports Main Event, available on Sky channel 401, will show the game live while Virgin Media customers can watch the action on channel 501.
How can I stream Kansas City Chiefs vs Washington Redskins live online?
If you’re unable to get in front of a TV, Sky Sports customers are able to watch the game live via Sky Go.
American viewers can catch the action online by heading to WatchESPN.
Week 5 results
New England Patriots 19-14 Tampa Bay Buccaneers
Cincinnati Bengals 20-16 Buffalo Bills
New York Jets 17-14 Cleveland Browns
Carolina Panthers 27-24 Detroit Lions
Indianapolis Colts 26-23 San Francisco 49ers
Miami Dolphins 16-10 Tennessee Titans
Los Angeles Chargers 27-22 New York Giants
Philadelphia Eagles 34-7 Arizona Cardinals
Jacksonville Jaguars 30-9 Pittsburgh Steelers