Pancreatic cancer linked to disrupted circadian clocks in cells

Circadian clock genes in almost all our cells follow regular 24-hour patterns, but can be disrupted by irregular sleep patterns and prolonged light exposure. Now these same disruptions have been found in the cells of cancerous pancreatic tissue

Health



11 January 2023

Pancreatic cancer cells captured via a coloured scanning electron micrograph

Pancreatic cancer cells captured via a coloured scanning electron micrograph

ANNE WESTON, FRANCIS CRICK INSTITUTE/SCIENCE PHOTO LIBRARY

Pancreatic cancer cells may have disrupted internal clocks that help to drive their spread. The discovery could pave the way for novel treatments for the condition, which has a five-year survival rate of just 11 per cent in the US.

Nearly every cell in our body contains molecular clocks that allow them to carry out biological processes in regular 24-hour cycles, known as circadian rhythms. These clocks are partly set by changes in light across days and nights.

Previous studies …

source: newscientist.com