Footage shared from Clayton County shows a large police presence in the area after the department confirmed two officers have been shot.
WSB-TV reports one of the injured officers is in critical condition and the other has sustained non-life-threatening injuries.
The Atlanta-based news outlet has also said police have described the shooting as “serious”.
Police revealed they were called to Highway 42 and I-675 on Tuesday night.
However, it is not yet clear what incident led them to the Rex area.
Separate reports suggest the suspect could be dead but WSB-TV claims police have not commented on potential suspects.
A nearby video ring doorbell appeared to capture the moment shots were fired.
In a clip uploaded to social media a barrage of gunfire can be heard for around 10 seconds.
Speaking about the incident, local resident Crystal Walker said: “We just heard an array of gunshots and sirens coming from every direction, it was crazy.”
Ms Walker added she was “most definitely” scared during the incident.
Ambulances left the scene and headed down to Grady Memorial Hospital.
Police agencies from neighbouring counties have reportedly arrived at Rex to offer assistance.
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