McFly star Tom Fletcher is also in the running to leave the competition on Sunday.
Betfair spokesperson Sam Rosbottom said: “The betting suggests Dan Walker’s time on Strictly may finally be up, as he is the 11/8 favourite to foxtrot away from the ballroom this weekend having somehow managed to avoid a dance-off on the show to date.
“But the breakfast presenter is only slightly ahead of Tilly Ramsay at 7/4 who has been in the last two dance-offs and found herself reprieved by the judges.
“If there is strong competition in the betting to be voted off, the same cannot be said for the winner’s odds with Rose Ayling-Ellis still the overwhelming 2/9 odds-on favourite to lift the glitterball trophy – the EastEnders actress’ odds becoming even shorter after her stunning routine last weekend.”
Strictly Come Dancing airs on Saturday at 6.35pm on BBC One.