Owen Farrell’s COVID and injury related tribulations this November continue as he misses out today due to an ankle injury. This means Courtney Lawes takes over as captain, Marcus Smith remains at stand-off, Manu Tuilagi is back in the centre and Harlequins’ Joe Marchant is on the wing.
In the forwards, last week’s tryscoring sub Jamie Blamire starts in place of the crocked Jamie George. Nic Dolly is the hooker on the bench.
South Africa bring back Handre Pollard to the ten shirt, partnering Cobus Reinach, and Lood De Jager starts at lock.
England: Freddie Steward; Joe Marchant, Henry Slade, Manu Tuilagi, Jonny May; Marcus Smith, Ben Youngs; Bevan Rodd, Jamie Blamire, Kyle Sinckler, Maro Itoje, Jonny Hill, Courtney Lawes (captain), Sam Underhill, Tom Curry.
Replacements: Nic Dolly, Joe Marler, Will Stuart, Charlie Ewels, Sam Simmonds, Alex Dombrandt, Raffi Quirke, Max Malins.
South Africa: Willie le Roux; Jesse Kriel, Lukhanyo Am, Damian de Allende, Makazole Mapimpi; Handré Pollard, Cobus Reinach; Ox Nché, Bongi Mbonambi, Trevor Nyakane, Eben Etzebeth, Lood de Jager, Siya Kolisi (captain), Kwagga Smith, Duane Vermeulen.
Replacements: Malcolm Marx, Steven Kitshoff, Vincent Koch, Franco Mostert, Jasper Wiese, Herschel Jantjies, Elton Jantjies, Frans Steyn.