The in-form Diogo Jota starts ahead of Roberto Firmino, while Naby Keita is surprisingly preferred to Thiago Alcantara, Curtis Jones and James Milner in midfield.
Real Madrid, who have been dabbling with a back three of late, look to have reverted to 4-3-3. Eder Militao and Nacho are covering for Sergio Ramos and Raphael Varane at centre-back.
Real Madrid (4-3-3) Courtois; Lucas Vazquez, Eder Militao, Nacho, Mendy; Modric, Casemiro, Kroos; Asensio, Benzema, Vinicius Jr.
Substitutes: Lunin, Altube, Marcelo, Valverde, Odriozola, Isco, Mariano Diaz, Rodrygo, Arribas, Chust.
Liverpool (4-3-3) Alisson; Alexander-Arnold, Phillips, Kabak, Robertson; Wijnaldum, Fabinho, Keita; Salah, Mane, Jota.
Substitutes: Adrian, Davies, Thiago, Milner, Firmino, Oxlade-Chamberlain, Jones, Tsimikas, Shaqiri, Davies, R Williams, Cain.
Referee Felix Brych (Germany).