Andy Farrell makes seven changes to the Ireland side that lost to France a couple of weeks ago. The Leinster wing James Lowe wins his first cap and the scrum-half Jamison Gibson-Park replaces Conor Murray to win his third cap.
Peter O’Mahony, Iain Henderson and Josh van der Flier return with Chris Farrell replacing Bundee Aki in the centres. The 22-year-old hooker Rónan Kelleher will start a Test for the first time with the uncapped Ulster fly-half Billy Burns on the bench.
For Wales and Wayne Pivac, Justin Tipuric is the only change to the side that lost to Scotland. The Bath fly-half Callum Sheedy is in the squad for the first time, while George North will win his 100th cap as and when he comes off the replacements’ bench.
Ireland: H. Keenan, A. Conway, C. Farrell, R. Henshaw, J. Lowe, J. Sexton, J. Gibson-Park; E. Byrne, R. Kelleher, A. Porter, Q Roux, J. Ryan, P. O’Mahony, J. van der Flier, C. Doris. Replacements: D. Heffernan, E. Byrne, F. Bealham, T. Beirne, W. Connors, C. Murray, B. Burns, K. Earls.
Wales: L. Halfpenny; L. Williams, J. Davies, O. Watkin, J. Adams; D. Biggar, G. Davies; R. Carre, R. Elias, T. Francis, W. Rowlands, A. W. Jones, S. Lewis-Hughes, J. Tipuric, T. Faletau. Replacements: E. Dee, W. Jones, S. Lee, J. Ball, A. Wainwright, L. Williams, C. Sheedy, G. North.