The World Cup hero will not play against Australia as Joe Root has named his side.
Archer is cut from the original squad as well as Sam Curran and Olly Stone ahead of the first game in the five-match Ashes series.
Chris Woakes has been given the nod as the third seamer alongside Stuart Broad and James Anderson.
Moeen Ali will provide the spin option while Ben Stokes is the all-rounder who will be expected to deliver for Root’s side.
Jason Roy has been given the nod to open the battling alongside Rory Burns who will be desperate to impress after a disappointing outing against Ireland last week.
Joe Root – England’s best player – moves up to No 3 in the order despite not enjoying that position.
Joe Denly is at No 4 and will be followed by the explosive middle order of Jos Buttler, Stoke and wicket-keeper Jonny Bairstow.
England will be desperate to beat Australia after losing the last Ashes series 4-0 back in 2017/18.
Australia legend Glenn McGrath believes Archer has a huge future for England in Test cricket though.
Asked by Express Sport whether he can grow into an attack leader, McGrath said: “I think he can, he seems to have a really good temperament.
“He’s got a very natural, very easy action. Just runs in, can generate good pace, good control and good bounce.
“He’s got a massive future in front of him and if he’s 100 per cent fit they should play him.”
McGrath believes Archer will learn a lot from playing alongside Broad and Anderson eventually.
He explained: “It will be important for guys like Jimmy and Broady to give a bit of advice to Jofra.
“He’s done so well at one-day cricket but Test cricket is so different.
“You have to go about it differently but if you can adapt to the change then he will do well.
“But the senior players will need to help him out too.”
England team for first Ashes Test: Rory Burns, Jason Roy, Joe Root (c), Joe Denly, Jos Buttler, Ben Stokes, Jonny Bairstow, Moeen Ali, Chris Woakes, Stuart Broad, James Anderson.