Vicky hit the headlines in 2014 after she underwent ground breaking sinus surgery at Chester Zoo – in what was the first time the procedure had been carried out in the UK.
She gave birth to two healthy daughters, Cherie in 1997 and Summer in 2002, who remain at Blackpool Zoo.
Darren Webster, zoo director at Blackpool Zoo, said: “It is with great sadness that we can confirm that Vicky, one of our beloved orangutans, has passed away.
“Vicky has battled with a chronic condition, called air sacculitis, for 15 years and was the first Bornean orangutan to undergo successful groundbreaking double surgery in UK history.
“She was also the first orangutan to be born at Blackpool Zoo and her arrival in 1984 was cause for huge celebration for staff, keepers and conservationists responsible for the species, which was declared critically endangered in 2016.
“Vicky gave birth to two healthy daughters, Cherie in 1997 and Summer in 2002, who remain at Blackpool Zoo with another female, Jingga and our male Ramon.
“She was a hugely popular member of our zoo family and was dearly loved by all of our visitors.
“Staff and keepers are extremely saddened at her passing and are being comforted by the kind messages of condolence we are receiving.
“Vicky, and her smile, will be missed by all.”