Cesc Fabregas, Andreas Christensen and Callum Hudson-Odoi could all be set for moves away from Stamford Bridge while Liverpool are also looking to clear out their squad.
Arsenal are eying Roma winger Cengiz Under while Southampton stalwart Steven Davis is said to be nearing a return to Rangers.
Barcelona are on the hunt for new signings with Frenkie de Jong most likely to arrive at the Nou Camp this month, although Paris Saint-Germain are also interested.
Manchester United, Real Madrid and Leeds United are all backed to get busy in the transfer market but what are the top 20 most likely deals to be completed in January, according to Football Whispers?
(1 – unlikely, 5 – very likely)
Domenico Berardi (Sassuolo) to Roma – 3.9
Steven Davis (Southampton) to Rangers – 4.0
Cesc Fabregas (Chelsea) to AC Milan – 4.0
Thorgan Hazard (Borussia Monchengladbach) to Atletico Madrid – 4.0
Moise Kean (Juventus) to Leeds United – 4.0
Andy King (Leicester City) to West Bromwich Albion – 4.0
Alberto Moreno (Liverpool) to Marseille – 4.0
Tanguy N’Dombele (Lyon) to Barcelona – 4.0
Emiliano Sala (Nantes) to Fulham – 4.0
Martin Skrtel (Fenerbahce) to Rangers – 4.0
Andreas Christensen (Chelsea) to Barcelona – 4.1
Douglas Costa (Juventus) to Manchester United – 4.1
Callum Hudson-Odoi (Chelsea) to Bayern Munich – 4.1
Frankie de Jong (Ajax) to Paris Saint-Germain – 4.1
Christian Pulisic (Borussia Dortmund) to Chelsea – 4.1
Cengiz Under (Roma) to Arsenal – 4.1
Brahim Diaz (Manchester City) to Real Madrid – 4.3
Fernando Llorente (Tottenham Hotspur) to Galatasaray – 4.3
Frankie de Jong (Ajax) to Barcelona – 4.5
Dominic Solanke (Liverpool) to Crystal Palace – 4.7