Manchester United head into their final Champions League group stage game against Valencia knowing they have already qualified for the knockout rounds.
The Red Devils secured a place in the Round of 16 with a narrow 1-0 victory over Young Boys.
Jose Mourinho will be keen to rest several first-team stars given the number of injury problems plaguing his squad.
Rotation means out-of-favour Paul Pogba will be given a chance to impress Mourinho in Spain.
The French midfielder has fallen down the pecking order in recent weeks after a patchy opening half of the 2018/19 campaign.
Pogba is likely to be given place in the team alongside summer signing Fred and cult-hero Marouane Fellaini.
Former Valencia midfielder Juan Mata is set to start as an opponent at the Mestella for the first time since 2011/12.
The popular star will be given a hero’s welcome on his return as he partners Romelu Lukaku and Marcus Rashford in attack.
Nemanja Matic is one booking away from a suspension and will not be risked in the game.
Victor Lindelof and Alexis Sanchez are ruled out, while Marcos Rojo, Antonio Valencia and Sergio Romero will be given chances to shine.
Predicted Manchester United team vs Valencia
(4-3-3) Romero; Valencia, Bailly, Rojo, Darmian; Fred, Fellaini, Pogba; Mata, Lukaku, Rashford.