The US leader is undertaking a week of rallies in five states starting on Saturday in a bid to secure the support of Republican voters ahead of the crunch midterm elections taking place in November.
President Trump spoke in Wheeling, West Virginia on Saturday night, where Republicans are seeking to unseat Democratic Senator Joe Manchin with Republican candidate Parick Morrissey.
In a direct attack on the Democratic Party, he said: “The Democratic Party will stop at nothing to run our lives, runs own your values and ransack our nation’s wealth.
“They will turn it around, make it bad so fast.
“And they’re determined to take back power by any means necessary.
“You see the meanness, the nastiness. They don’t care who they hurt, who they have to run over to get power.”
The US leader mimicked the Democrats’ liberal attitudes to issues including border control, tax and crime in a mocking statement.
He said: “We want open borders, we want high taxes, we want crime, because basically they’re saying – they have crime, they have high taxes, they have open borders, and by the way, we don’t want to fund the military.”
President Trump also used his address to respond to the fractious confirmation hearings of Supreme Court nominee Brett Kavanaugh.
He branded Mr Kavanaugh an “accomplished legal mind” with a “sterling record of public service”, despite facing accusations of sexual misconduct by at least three women.
President Trump said: “On Thursday the American people saw the brilliant and quality and courage of our nominee for the United States Supreme Court Judge Brett Kavanaugh.
“A vote to confirm Judge Kavanaugh is a vote to confirm one of the most accomplished legal minds of our time, a jurist wit a sterling record of public service.”
He argued that Mr Kavanaugh had endured “the meanness, the anger” of the Democratic Party.
He concluded: “A vote for Judge Kavanaugh is a vote to reject the ruthless and outrageous tactics of the Democratic Party.”
The US leader used his address to underline the significance of the upcoming elections, branding them the “most important in our lifetimes”.
He also warned his supporters that the legislative victories the Republicans have achieved are “at stake in November”.
President Trump will hold further rallies in Johnson City, Tennessee on Monday, in Southaven, Mississippi on Tuesday, in Rochester, Minnesota on Thursday, and in Topeka, Kansas next Saturday.