Mangkhut is currently expected to make landfall in the northern part of the Philippines on Saturday.
Ten million people are in the weather system’s path and thousands of people have already begun evacuating.
Schools and offices are being closed and farmers are also racing to save crops.
Manuel Mamba, governor of the northeastern province of Cagayan, said: “What’s happening now is pre-emptive evacuation in certain areas.
“There are no people on the streets as they are preparing for the storm.”
A £23billion relief effort has been put into effect by authorities as concern is growing over the typhoon still gathering strength on its path towards the East Asian country.
Mangkhut, also known as Ompong in the Philippines, reached super typhoon status on Tuesday evening and is the equivalent of a Category 5 hurricane.
A report issued by AccuWeather said if the typhoon remains on its current track, the worst impacts will be felt on the northern tip of the main island of Luzon as well as the islands of Batanes and Babuyan Islands, Philippines.
Typhoon Mangkhut path tracker LIVE: THOUSANDS evacuate – Philippines ready for strike
The report said: “As Mangkhut pushes westward and emerges into the South China Sea, it may weaken slightly; however, it is expected to at the very least remain a powerful typhoon.”
Northern Luzon was also devastated in 2016 by Super Typhoon Haima, where 14,000 houses were destroyed and 50,000 homes damaged.
Mangkhut will also bring flooding, heavy rainfall and damaging winds to Taiwan and China into early next week according to the latest forecast.
AccuWeather urges residents from the northern Philippines into Taiwan as well as those in southern China and northern Vietnam to “continue to closely monitor the track of Mangkhut and make preparations.”
From Friday throughout Sunday Typhoon Mangkhut can cause impacts such as damaging winds, flooding rainfall, mudslides, coastal flooding and travel disruptions.
Local authorities said they expect storm surges of up to 23 feet and are warning that heavy rains could trigger flash flooding and landslides.
Rainfall amounts between 6-10 inches are possible and can pose a serious threat to lives and property.
The country’s deadliest storm on record is super typhoon Haiyan, which killed more than 5,000 people and affected millions in 2013.
Haiyan was a Category 5 storm with maximum sustained winds of 195mph.
If Typhoon Mangkhut strikes the Philippines as a Category 5 storm, catastrophic damage and life-threatening conditions will occur.
According to the National Hurricane Center a high percentage of framed homes will be destroyed and fallen trees and power poles will completely isolate residential areas.
Power outages can also last for weeks, possibly months and most areas will be uninhabitable for weeks or months.