His words have come as the latest exit polls show that the eurosceptic Five Star Movement is now the single largest party in the election.
Mr Farage tweeted: “Congratulations to my colleagues in the European Parliament Five Star Movement for topping the poll tonight.”
He also retweeted a video posted by the Five Star Movement of its party representatives celebrating a results projection.
Meanwhile, exit polls have also shown that former prime minister Silvio Berlusconi’s centre-right party and his far-right eurosceptic allies, Lega, could emerge as the largest bloc in parliament but fall short of a majority.
The former Ukip leader is not the first anti-EU MEP to revel in what they consider to be the success of eurosceptic parties in today’s Italian election.
Marine Le Pen has also taken to Twitter to taunt the EU ahead of the what she says will be a “terrible evening” for the crumbling Brussels bloc.
The anti–EU former French presidential candidate tweeted: “The European Union is going to have a terrible evening… #Italie #Elezioni2018.”
Italian voters look set to send a stern warning to the European Union as the country goes to the poll with “disappointment” in Brussels’ establishment continuing to grow.
The recent campaign has been “more populist and more anti-EU” than any other election in Italian history.
Eurosceptic voices not only lead a number of the major parties, including Lega and the Five Star Movement but also have a strong representation in Silvio Berlusconi’s Forza Italia.
Political risk analyst Raffaella Tenconi suggested voters will use the Italian election 2018 to send a clear message to the European Union higher echelons.
She said: “It’s true that love towards the EU has significantly decreased.
“The Italian electorate is simply saying that the structural changes that have been done, the implementation policies and the type of policies that have been done are nor optimal for the state of the economy today.”
Ms Tenconi, however, estimated it would take years for Italy – a co-founder and one of the largest contributors to the EU – to effectively decide to break up with Brussels.
She told Bloomberg: “Disillusionment about the current state of the EU has significantly increased but between now and actually desiring to leave the euro area as priority number one I think is really a tiny minority.”
A recent study revealed 51 percent of Italians would be in favour of leaving the EU – with young citizens holding the worst opinion about the impact of the EU on their country.