Researchers profiled the epigenomic landscape of Alzheimer’s brains, specifically in one of the regions affected early in AD, the lateral temporal lobe. They compared these to both younger and elderly cognitively normal control subjects. The team described the genome-wide enrichment of a chemical modification of histone proteins that regulates the compaction of chromosomes in the nucleus. Changes along the genome in disease versus normal aging brains may signify places for future drug development.
You may also like
Egyptian archaeologists have discovered ancient tombs containing mummies with golden tongues in their mouths – a possible mythological token to the afterlife. Authorities […]
Work for a horrible boss? You could end up being just as bad – as hostile behaviour at the top of an […]
Since my youth, I have been spellbound by the spectacle of nature and the wondrous array of species which call Earth home. […]
Archaeologists who uncovered traces of a city’s Roman and medieval past under what is now a city shopping centre are up for […]