The striker has found game time hard to come by at Manchester United since the arrival of Alexis Sanchez.
And Sanchez starts alongside Romelu Lukaku and Anthony Martial today.
But Rashford’s omission from the bench is a talking point after a stunning rise from the youth side to the first team.
This is the first time all season that he has not been named in a match squad.
But why is he not involved today?
ESPN FC report that Rashford picked up a knock last week against Huddersfield and was being monitored.
United were said to be hopeful he would be passed fit to play, but he hasn’t made it.
And Mourinho confirmed both Rashford and Ander Herrera had injuries but shouldn’t be out too long.
“Injured both,” he said when asked why they missed out on Sky.
“I don’t think long term, lets wait a little bit. Little ticks in muscles, not possible today.”
Zlatan Ibrahimovic remains out meaning United do not have a striker on the bench.
Jose Mourinho will be able to call on three defenders – Victor Lindelof, Marcos Rojo and Luke Shaw – as well as midfielders Michael Carrick, Scott McTominay and Juan Mata from the bench if needed.
Jamie Redknapp this week described the Sanchez signing as a sledgehammer to Rashford’s career.
“I don’t blame Manchester United for bringing in Alexis Sanchez,” he told Sky Sports.
“His wages are expensive, but you would normally have to pay around £70m for a player like that in the current market. They have dodged the transfer fee and signed a winner who will give them fantastic energy and quality.
“On the other side of it, though, I can’t help but feel disappointed about what it does to a player like Marcus Rashford. Some would say that great players come and go and you’ve got to get on with it, but the bottom line is that Rashford has now dropped down the pecking order.
“That’s what football is like. When I signed for Liverpool at the age of 17, I went straight ahead of all the other players in the youth team because I had been bought in from outside.
“It’s the same with Sanchez now. Due to his reputation and the fact he has been bought by the manager, Sanchez will always go ahead of Rashford whether he is playing better or not.
“It’s the hardest thing for a young English player. You feel like you are just getting to the top of the pecking order and then suddenly, bang, it’s like a sledgehammer hits you. Your club have signed a world star.”