In addition to the prizegiving, there will also be a wide range of performances – so who will be taking to the stage?
Viewers will have a lot to look forward to – so here’s your guide to everyone who’s set to sing this evening.
Lady Gaga, Pink and Bruno Mars featuring Cardi B will be three of the most anticipated for pop fans, with the latter duo set to dust off their recent smash hit Finesse.
Kesha is also set to grab the mic for a rendition of Praying, on which she’ll be joined by Camila Cabello, Cyndi Lauper, Julia Michaels, and Andra Day.
Kendrick Lamar, Childish Gambino, Little Big Town, Ben Platt, SZA and U2 are expected to perform at some point in the evening, as are Sam Smith, Sting, and Jon Batiste and Gary Clark Jr.
There’ll be a tribute to the victims of the 2017 Las Vegas shooting from Eric Church, Maren Morris and Brothers Osborne, and Logic, Alessia Cara and Khalid will sing their acclaimed track 1-800-273-8255; the title of which is the phone number of the US National Suicide Prevention Lifeline.
Elsewhere, DJ Khaled, Rihanna and Bryson Tiller should generate plenty of attention as they perform Will Thoughts, while Luis Fonsi and Daddy Yankee will perform one of 2017’s most successful songs: Despacito, with Zuleyka Rivera.
Elton John will team up with Miley Cyrus, Chris Stapleton with Emmylou Harris and Zedd with Maren Morris and Grey.
Finally, Patty LuPone is due to sing Don’t Cry For Me Argentina.
2017 marks the 60th Grammy Awards, with James Corden returning as host.
Jay Z has the most nominations, with eight.