Tom Selleck as Peter Mitchell
Selleck was a pin-up when he joined the movie and he’s continued to have a successful career.
It’s TV work that’s kept him primarily in the public eye: Magnum, PI came to an end soon after this film came out, and then he played Dr Richard Burke in Friends for an iconic string of episodes.
Since 2010 he’s been the lead in Blue Bloods, racking up over 150 episodes.
Steve Guttenberg as Michael Kellam
Now 59, Guttenberg hasn’t done many high-profile roles but his career has been consistent – he was in Veronica Mars in a recurring role and a cluster of TV movies.
Guttenberg is also a comedian, producer and director – so it’s safe to say he’s been kept very busy.
Ted Danson as Jack Holden
Now 70, Ted is undergoing a career resurgence thanks to his role as Michael in The Good Place, one of the most critically acclaimed comedies of recent years.
In fact, TV is where Danson has been busiest over the years since Three Men and a Baby; including roles in Curb Your Enthusiasm, Damages, Bored To Death and – most notably – CSI.
Margaret Colin as Rebecca
Collin, now 59, will be most familiar to audiences nowadays as Blair Waldorf’s mother Eleanor in Gossip Girl.
She’s also had roles in Veep, Shades of Blue, The Good Wife and Nurse Jackie.
Celeste Holm as Mrs. Holden
Holm died in 2012 at the age of 95.
She slowed down her career later in life but made appearances in the likes of Whoopi, Cheers and Alchemy in the years since Three Men and a Baby.
Nancy Travis as Sylvia Bennington
Three Men… was one of Travis’ first film roles, and she’s barely stopped since.
Currently she’s known to US audiences as Vanessa Baxter in the sitcom Last Man Standing, for which she has filmed over 100 episodes since 2011.
She’s also been in Becker, Desperate Housewives, The Jane Austen Book Club, and How I Met Your Mother.
Michelle and Lisa Blair as Baby Mary
Lisa Blair and Michelle Blair Ontonovich took turns playing little Mary, but didn’t star in any more films.
Their mother said she was “bored at home” when the casting call came about, and they haven’t starred in any movies since.