The live stream above will show SpaceX’s historic resupply mission to the ISS which is scheduled for 3.36pm GMT (10.36am EST).
SpaceX will launch a recycled Falcon 9 rocket in tandem with a Dragon spacecraft previously used in a 2015 mission.
The space company said: “This mission marks the first time SpaceX is flying both a flight-proven Falcon 9 and a flight-proven Dragon spacecraft.
“Falcon 9’s first stage previously supported the CRS-11 mission in June 2017 and the Dragon spacecraft previously supported the CRS-6 mission in April 2015.”
On Tuesday the aerospace manufacturer said it was “targeting” Wednesday December 13 for the mission dubbed CRS-13, but the date was later postponed. It was originally planned for Friday December 8.
Weather forecasters have now given the all clear for today’s launch window thanks to cloudy but warm conditions. The Falcon is expected to dock with the ISS by Sunday.
Since successfully delivering the Koreasat-5A satellite in October, SpaceX’s launch schedule has had a long hiatus of over a month.
The Falcon 9 will blast off from the Space Launch Complex 40 (SLC-40) at the Cape Canaveral Air Force Station.
The 17th launch of the year also marks SpaceX’s return to SLC-40 after a fiery explosion on the pad tore through a Falcon 9 in April 2015.
The flight will deliver a cargo packed with over two tonnes of essential survival supplies and research equipment to the ISS on board the free-flying Dragon spacecraft.
The Dragon will then stay attached to the ISS for about a month before it leaves orbit to land down in the Pacific Ocean just off the coast of Baja California.
WATCH: NASA ISS LIVE STREAM
The Falcon 9 itself will attempt to land at SpaceX’s Landing Zone 1 (LZ-1) in Cape Canaveral upon reentry into the atmosphere.
It is the 13th of 20 planned resupply missions contracted out to SpaceX by NASA.
SpaceX said: “Under the CRS contracts, SpaceX has restored an American capability to deliver and return significant amounts of cargo, including live plants and animals, to and from the orbiting laboratory.
“A variant of the Dragon spacecraft, called Crew Dragon, is being developed for US-based crew transport to and from the space station.”