The former Playboy model and actress pulled no punches in conversation with TV presenter Megyn Kelly.
Anderson said that she was not surprised when allegations against Weinstein were made public.
“I think it was common knowledge that certain producers and certain people in Hollywood are people to avoid. Privately.
“You know what you’re getting into if you go to a hotel room alone,” she added.
Kelly said that since many of the meetings had been set up by agents, it was surely fair to believe that the rendezvous was safe.
Anderson replied: “Send somebody with them, that’s what they should have done.
“I just think there’s easy ways to remedy that, that’s not a good excuse.”
Anderson, 50, then revealed that she was was the subject of a number of unwanted sexual advances from leading figures in Hollywood, but refused them.
She added: “When I came to Hollywood, of course I had a lot of offers to do private auditions and things that made absolutely no sense; don’t go into a hotel room alone; if someone answers the door in a bathrobe, leave. You know, common sense.
“Hollywood is very seductive, and people want to be famous.”
Her comments sparked outrage with feminist groups but Anderson, who has been public about being a victim of sexual abuse herself, has stood by her views and slammed so-called “victimhood feminism”.
She wrote in a letter to TMZ: “I think this narrative of ‘victim blaming’ and ‘lack of solidarity’ is trying to coerce me [and others] into consensus on something that should be debated and discussed broadly.
“This exactly what I am saying is a problem with the contemporary ‘victimhoood feminism’.
“The people who subscribe to that notion tolerate and actually expect women to talk about the stories of abuse and experiences with creeps.
“But they would NOT tolerate a woman with her own opinion. So pathetic.”