Wenger has made 11 changes from the 2-0 win over Tottenham last weekend, swapping out his entire team with knockout qualification already secured.
Olivier Giroud, Danny Welbeck and Jack Wilshere start as a front three while Ashley Maitland-Niles is given the left wing-back role.
A youthful bench includes Joe Willock, Reiss Nelson and Eddie Nketiah as Wenger looks to give his academy graduates valuable experience.
Arsenal fans have made it clear they would have liked to see these rising stars given a starting role against Cologne, while they have also called into question the manager’s tactical choices – particularly Calum Chambers starting at right wing-back while Mathieu Debuchy is picked in central defence.
Scroll through the gallery above to see some of the best reactions from fans to the Arsenal team ahead of their match against Cologne.