The outbreak of plague has slowed in recent days but could escalate again if money isn’t found to contain the outbreak.
There have been 2,034 of cases of plague in Madagascar recorded since August 1 and 165 people had died on the African island.
An update from the WHO said: “While progress has been made to control the outbreak of plague in Madagascar, the possibility of future flare-ups cannot be ruled out.
“Notwithstanding the financial support and contributions from partners, WHO urgently requires an additional $4million (£3m) to sustain response operations in the next three months of the plague outbreak in Madagascar.
“The funding is needed to interrupt ongoing transmission, provide care for those affected by the disease, reduce the risk of international spread and provide effective coordination and operations support.”
All schools in the country had been disinfected and 8,000 community leaders had been trained to spot signs of the disease, the WHO said.
They warned the majority of regions in Madagascar, 14 of 22, had been hit by the outbreak.
Currently 10 countries have been put on alert about the virus, with Malawi, South Africa, Ethiopia, Kenya, Mozambique, Seychelles, Tanzania, La Reunion, Mauritius and Comoros Islands all being told to prepare.
But in more positive news, the WHO said no new suspected cases of pulmonary plague had been recorded since November 7. No deaths had been reported in that time either.
The UK foreign office said, while plague outbreaks occur annually in Madagascar, the flare-ups in urban areas were not common.
Their travel advisory report said: “There is currently an outbreak of pneumonic and bubonic plague in Madagascar.
“Outbreaks of plague tend to be seasonal and occur mainly during the rainy season, with around 500 cases reported annually.
“Whilst outbreaks are not uncommon in rural areas, the latest outbreak has seen an increase in reported cases in urban areas, including Antananarivo.”