Spurs will be playing their fourth match of a six-game home run, and go into the clash on the back of a 112-95 victory over the Phoenix Suns on Sunday.
LaMarcus Aldridge was in scintillating form that day, and top scored with 21 points.
Spurs (6-4) were down four points at half-time, but turned it around to win.
Speaking about their form, Spurs reserve forward Rudy Gay said: “In our last couple of games, our third quarters have been kind of slow.
“We had to come out with intensity. We made a couple of defensive changes, and we had the mindset to come out there and win the game in the third quarter.”
Meanwhile, as far as the Clippers are concerned, DeAndre Jordan has been their standout player.
With an average of 7.1 defensive rebounds and 1.3 blocks, he has been a consistent performer.
How to watch Los Angeles Clippers vs San Antonio Spurs on TV?
Tonight’s action tips off at 1.30am GMT, and it is being broadcast on BT Sport 1 which is channel 413.
BT Sport is the exclusive home of the NBA in the UK for the 2017/18 season.
They will broadcast up to seven lives games per week throughout the regular season and the first and second rounds of the playoffs, as well as every game of the conference finals and NBA Finals.
How to watch LA Clippers vs San Antonio Spurs online?
If you’re unable to get in front of a TV, BT Sport customers are able to watch the game live via the app.
Alternatively you can sign up for the NBA League Pass with the option of a day pass.
The NBA League Pass lets you watch (almost) every NBA game depending on the package you select.
American viewers can catch the action online by also going for the NBA League Pass.