And the striker could also be a major doubt for next Wednesday’s Champions League clash with Real Madrid.
The Spurs top scorer is having round the clock treatment on the hamstring injury he picked up during last Sunday’s’s 4-1 win over Liverpool at Wembley.
Pochettino left his top scorer out of the team that lost 3-2 to West Ham after being two goals ahead in the Carabao Cup at Wembley on Wednesday night.
But Kane, who has scored 15 goals in his last 15 games, is not responding as quickly to treatment as was expected.
Pochettino withdrew Fernando Llorente, the only other natural centre-forward in his squad, with 20 minutes remaining against West Ham on Wednesday, despite trailing by a goal. The move looked like a precaution, with tomorrow’s key game in mind.
Asked if Kane would be fit, Pochettino said only: “We’ll see. We need to assess the team. We were forced to rotate on Wednesday for different reasons.”