Manchester United can go clear at the top of the table – albeit for a short time – with a win or draw over Crystal Palace.
United and Manchester City are level on points at the top of the tale, with their rivals playing Chelsea in the late kick off.
United have won five on the bounce and face a Crystal Palace side who are yet to score this season.
Meanwhile, Bournemouth host Leicester and Stoke play against Southampton.
Watford travel to West Brom, while West Ham and Swansea clash in east London.
Premier League 3pm fixtures
Bournemouth vs Leicester
Manchester United vs Crystal Palace
Stoke vs Southampton
West Brom vs Watford
West Ham vs Swansea
Manchester United vs Crystal Palace LIVE
Manchester United vs Crystal Palace lineups
Romelu Lukaku starts for Manchester United after passing a late fitness test.
But Eric Bailly moves to the bench amid five changes for United.
Antonio Valencia, Phil Jones, Juan Mata, Marouane Fellaini and Marcus Rashford come into the XI.
Man Utd: De Gea, Valencia, Jones, Smalling, Young, Matic, Fellaini, Mata, Mkhitaryan, Rashford, Lukaku.
Crystal Palace: Hennessey, Ward, Sakho, Delaney, Van Aanholt, Townsend, Milivojevic, Cabaye, Schlupp, Puncheon, Sako.
Manchester United vs Crystal Palace form
Manchester United head into this clash having won five on the bounce. They haven’t lost since going down 2-1 to Real Madrid in the UEFA Super Cup.
United have scored exactly four goals in three of their last four games.
They play a Palace side leaking goals at the back and unable to score at the other end.
Palace are without Christian Benteke today… just to make life harder for boss Roy Hodgson.
Premier League 3pm teams
Bournemouth vs Leicester:
Bournemouth: Begovic, Daniels, Ake, Francis, Smith, Pugh, Surman, King, Cook, Stanislas, Defoe.
Leicester: Schmeichel, Simpson, Morgan (c), Maguire, Fuchs, Albrighton, Ndidi, King, Gray, Okazaki, Vardy.
Stoke vs Southampton:
Stoke: Butland; Zouma, Cameron, Wimmer; Diouf, Allen, Fletcher, Pieters; Shaqiri, Choupo-Moting; Berahino.
Southampton: Forster, Cedric, Van Dijk, Yoshida, Bertrand, Romeu, Lemming, Tadic, Davis, Redmond, Long.
West Brom vs Watford:
West Brom: Foster, Gibbs, Evans, Rondon, Phillips, Brunt, Barry, Rodriguez, Krychowiak, Dawson, Hegazi.
Watford: Gomes (GK); Femenía, Mariappa, Kabasele, Holebas; Doucouré, Capoue; Carrillo, Cleverley, Richarlison; Deeney (C).
West Ham vs Swansea:
Hart, Zabaleta, Reid, Fonte, Cresswell, Kouyate, Noble, Antonio, Ayew, Hernandez, Carroll.
Swansea: Fabianski, Naughton, Fernandez, Mawson, Olsson, Britton (C), Sanches, Carroll, Ayew, Bony, Abraham.
Welcome
Hello and welcome to our live coverage of Manchester United vs Crystal Palace.
We’ll be focusing on events at Old Trafford for the large part today.
But we’ll also bring you all the score updates from around the Premier League.