Eman Abdul Atti died this morning at Burjeel hospital in Abu Dhabi after years battling heart and kidney problems.
The Egyptian was bedridden for more than two decades and could not support her own weight standing up.
She was being treated by a team of 20 specialist doctors and had to be lifted from her home using a crane before being flown to hospital in a cargo plane.
She suffered from parasitic disease Elephantiasis and was constantly hungry as a result.
A spokesperson said: “She had been under supervision of a medical team of over 20 doctors from different specialities who were managing her medical condition from the time she arrived in the UAE.
“Eman’s family expressed their appreciation for the care and treatment provided to her by Burjeel hospital.”
Anti weighed in at 11lbs when she was born, and by age 11 she could no support her own weight.