Moments before Mr Trump was due to make his debut UN speech, Pyonyang represtantive Ja Song Nam left the General Assembly hall in New York.
North Korea has confirmed they deliberately boycotted the President’s 41-minute speech, which did little to ease tensions between the two nations.
It is the latest spat in a war of words between North Korea and the US over Kim Jong-un’s nuclear ambition.
North Korean UN mission said a junior diplomat remained in the delegation’s front-row seat to hear Mr Trump describe the country’s leader as “Rocket Man” in another incendiary speech.
In an extraordinary delivery to the international peace-keeping organisation, Mr Trump said he would be forced to “totally destroy” North Korea if the rogue nation continued to develop nuclear weapons and threaten America.
He mocked North Korean leader Kim Jong-un, labelling him “rocket man” for his continued missile launches and nuclear tests in breach of UN orders.
Mr Trump said if America “is forced to defend itself or its allies, we will have no choice but to totally destroy North Korea.
“Rocket man is on a suicide mission for himself and his regime.”
The US President also warned America’s other rivals would “go to hell” for their actions before issuing a rallying cry for unity.
Mr Trump said: “We must work together against those who threaten with chaos and terror.
“No-one has shown more contempt for other nations and the wellbeing of their people than the depraved regime of North Korea.
“They respect neither their own citizens nor the sovereign rights of countries.
“If the righteous men do not confront the wicked few then evil will triumph.”
He added: “They are responsible for the starvation of millions of North Koreans.
“We want harmony and friendship, not hardship and struggle.”
The President’s verbal attack on Pyongyang drew mumbles from the UN General Assembly Hall, Reuters reported.
One man in the audience covered his face with his hands shortly after Trump made his “totally destroy” comment.
Swedish Foreign Minister Margot Wallstrom crossed her arms.