Cazorla has been out injured since October 2016 with an ongoing Achilles injury.
The Spaniard has had surgery eight times in a bid to solve the problem and has posting videos of himself running.
And though Wenger confirmed Cazorla will start running on the training pitch today, he admitted a return to the team is still months away.
He said: “He’s having his first run today. That’s quite positive. Flexibility is quite good.
“Difficult to predict when he will be back. Not before Christmas.
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“That’s why he’s not included in the Europa League.
“Not played for over a year, always cautious to set a date.”